type: position_score
table:
  filename: ENCFF784YVX.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR680OFU
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR680OFU [TISSUE: Homo sapiens HeLa-S3, TARGET: EP300]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\
    _internal\\_action**: Archived analysis {ENCAN443OCA|/analyses/ENCAN443OCA/} has\
    \ in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\
    \n**audit\\_warning**: Processed alignments file {ENCFF952XCP|/files/ENCFF952XCP/}\
    \ processed by ChIP-seq ENCODE3 hg19 pipeline has 17891090 usable fragments. The\
    \ minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ EP300-human and investigated as a transcription factor is 10 million usable\
    \ fragments. The recommended value is > 20 million, but > 10 million is acceptable.\
    \ (See {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\\
    _warning**: Replicate concordance in ChIP-seq experiments is measured by calculating\
    \ IDR values (Irreproducible Discovery Rate). ENCODE processed IDR thresholded\
    \ peaks files {ENCFF583XDA|/files/ENCFF583XDA/}, {ENCFF784YVX|/files/ENCFF784YVX/}\
    \ processed by ChIP-seq ENCODE3 hg19 pipeline have a rescue ratio of 1.67 and\
    \ a self consistency ratio of 2.72. According to ENCODE standards, having both\
    \ rescue ratio and self consistency ratio values < 2 is recommended, but having\
    \ only one of the ratio values < 2 is acceptable.\n\n**audit\\_warning**: Replicate\
    \ concordance in ChIP-seq experiments is measured by calculating IDR values (Irreproducible\
    \ Discovery Rate). ENCODE processed IDR thresholded peaks files {ENCFF240IVA|/files/ENCFF240IVA/},\
    \ {ENCFF803UTK|/files/ENCFF803UTK/} processed by ChIP-seq ENCODE3 hg19 pipeline\
    \ have a rescue ratio of 1.67 and a self consistency ratio of 2.72. According\
    \ to ENCODE standards, having both rescue ratio and self consistency ratio values\
    \ < 2 is recommended, but having only one of the ratio values < 2 is acceptable."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR680OFU
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens HeLa-S3
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0002791/
    perturbed: false
    doi: 10.17989/ENCSR680OFU
    date_created: '2014-07-02T22:44:17.707488+00:00'
    date_released: '2014-07-07'
    submitter_comment: As of March 5th, 2018, the Antibody Review Board has exempted
      this antibody, therefore releasing this experiment.
    target: EP300
