type: position_score
table:
  filename: ENCFF115RUG.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR502GAX
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR502GAX [TISSUE: Homo sapiens HepG2 genetically modified
    (insertion) using CRISPR targeting H. sapiens ZNF652, TARGET: ZNF652]'
  description: '**status**: released


    **biological\_replicates**: Rep 1, Rep 2


    **summary**: genetically modified (insertion) using CRISPR targeting H. sapiens
    ZNF652


    **output\_type**: optimal IDR thresholded peaks


    **audit\_internal\_action**: Archived analysis {ENCAN178ETB|/analyses/ENCAN178ETB/}
    has in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}


    **audit\_warning**: Processed alignments file {ENCFF054DOO|/files/ENCFF054DOO/}
    processed by ChIP-seq ENCODE3 hg19 pipeline has 19967055 usable fragments. The
    minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting
    ZNF652-human and investigated as a transcription factor is 10 million usable fragments.
    The recommended value is > 20 million, but > 10 million is acceptable. (See {ENCODE
    ChIP-seq data standards|/data-standards/chip-seq/} )


    **audit\_warning**: Replicate concordance in ChIP-seq experiments is measured
    by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed IDR
    thresholded peaks files {ENCFF004UHW|/files/ENCFF004UHW/}, {ENCFF115RUG|/files/ENCFF115RUG/}
    processed by ChIP-seq ENCODE3 hg19 pipeline have a rescue ratio of 1.42 and a
    self consistency ratio of 2.53. According to ENCODE standards, having both rescue
    ratio and self consistency ratio values < 2 is recommended, but having only one
    of the ratio values < 2 is acceptable.


    **audit\_warning**: Replicate concordance in ChIP-seq experiments is measured
    by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed IDR
    thresholded peaks files {ENCFF977AXL|/files/ENCFF977AXL/}, {ENCFF988KKJ|/files/ENCFF988KKJ/}
    processed by ChIP-seq ENCODE3 hg19 pipeline have a rescue ratio of 1.42 and a
    self consistency ratio of 2.53. According to ENCODE standards, having both rescue
    ratio and self consistency ratio values < 2 is recommended, but having only one
    of the ratio values < 2 is acceptable.'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR502GAX
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: genetically modified (insertion) using CRISPR targeting
      H. sapiens ZNF652
    biosample_summary: Homo sapiens HepG2 genetically modified (insertion) using CRISPR
      targeting H. sapiens ZNF652
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0001187/
    perturbed: false
    doi: 10.17989/ENCSR502GAX
    date_created: '2016-07-28T18:55:24.647001+00:00'
    date_released: '2016-11-08'
    submitter_comment: ''
    target: ZNF652
