type: position_score
table:
  filename: ENCFF976LBY.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR498TWD
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR498TWD [TISSUE: Homo sapiens HepG2 genetically modified
    (insertion) using CRISPR targeting H. sapiens MAF1, TARGET: MAF1]'
  description: '**status**: released


    **biological\_replicates**: Rep 1, Rep 2


    **summary**: genetically modified (insertion) using CRISPR targeting H. sapiens
    MAF1


    **output\_type**: IDR thresholded peaks


    **audit\_internal\_action**: Released analysis {ENCAN016HAY|/analyses/ENCAN016HAY/}
    has in progress subobject document {b52e1d2b-714d-4db5-bb91-131e5f03f6ef|/documents/b52e1d2b-714d-4db5-bb91-131e5f03f6ef/}


    **audit\_internal\_action**: Released analysis {ENCAN016HAY|/analyses/ENCAN016HAY/}
    has in progress subobject quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}


    **audit\_warning**: Replicate concordance in ChIP-seq experiments is measured
    by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed IDR
    thresholded peaks files {ENCFF976LBY|/files/ENCFF976LBY/} processed by ChIP-seq
    ENCODE4 v1.5.0 GRCh38 pipeline have a rescue ratio of 1.12 and a self consistency
    ratio of 2.39. According to ENCODE standards, having both rescue ratio and self
    consistency ratio values < 2 is recommended, but having only one of the ratio
    values < 2 is acceptable.


    **audit\_warning**: Replicate concordance in ChIP-seq experiments is measured
    by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed IDR
    thresholded peaks files {ENCFF925PQA|/files/ENCFF925PQA/} processed by ChIP-seq
    ENCODE4 v1.5.0 GRCh38 pipeline have a rescue ratio of 1.12 and a self consistency
    ratio of 2.39. According to ENCODE standards, having both rescue ratio and self
    consistency ratio values < 2 is recommended, but having only one of the ratio
    values < 2 is acceptable.'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR498TWD
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: genetically modified (insertion) using CRISPR targeting
      H. sapiens MAF1
    biosample_summary: Homo sapiens HepG2 genetically modified (insertion) using CRISPR
      targeting H. sapiens MAF1
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0001187/
    perturbed: false
    doi: 10.17989/ENCSR498TWD
    date_created: '2019-03-09T00:20:12.921050+00:00'
    date_released: '2020-07-14'
    submitter_comment: ''
    target: MAF1
