type: position_score
table:
  filename: ENCFF950YZE.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR000EHF
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR000EHF [TISSUE: Homo sapiens K562, TARGET: POLR2AphosphoS2]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: IDR thresholded peaks\n\n**audit\\_error**:\
    \ Processed alignments file {ENCFF733DZV|/files/ENCFF733DZV/} processed by ChIP-seq\
    \ ENCODE4 v1.6.1 GRCh38 pipeline has 4898284 usable fragments. The minimum ENCODE\
    \ standard for each replicate in a ChIP-seq experiment targeting POLR2AphosphoS2-human\
    \ and investigated as a transcription factor is 10 million usable fragments. The\
    \ recommended value is > 20 million, but > 10 million is acceptable. (See {ENCODE\
    \ ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_internal\\\
    _action**: Released analysis {ENCAN307CMP|/analyses/ENCAN307CMP/} has in progress\
    \ subobject document {c8364348-37c8-4f82-9ec3-6f68a1d94276|/documents/c8364348-37c8-4f82-9ec3-6f68a1d94276/}\n\
    \n**audit\\_internal\\_action**: Released analysis {ENCAN307CMP|/analyses/ENCAN307CMP/}\
    \ has in progress subobject quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}\n\
    \n**audit\\_not\\_compliant**: Processed alignments file {ENCFF083UKK|/files/ENCFF083UKK/}\
    \ processed by ChIP-seq ENCODE4 v1.6.1 GRCh38 pipeline has 6304888 usable fragments.\
    \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ POLR2AphosphoS2-human and investigated as a transcription factor is 10 million\
    \ usable fragments. The recommended value is > 20 million, but > 10 million is\
    \ acceptable. (See {ENCODE ChIP-seq data standards|/data-standards/chip-seq/}\
    \ )\n\n**audit\\_warning**: Replicate concordance in ChIP-seq experiments is measured\
    \ by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed\
    \ IDR thresholded peaks files {ENCFF950YZE|/files/ENCFF950YZE/} processed by ChIP-seq\
    \ ENCODE4 v1.6.1 GRCh38 pipeline have a rescue ratio of 1.37 and a self consistency\
    \ ratio of 2.22. According to ENCODE standards, having both rescue ratio and self\
    \ consistency ratio values < 2 is recommended, but having only one of the ratio\
    \ values < 2 is acceptable."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR000EHF
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens K562
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0002067/
    perturbed: false
    doi: 10.17989/ENCSR000EHF
    date_created: '2014-02-12T23:18:11.509752+00:00'
    date_released: '2011-10-29'
    submitter_comment: ''
    target: POLR2AphosphoS2
