type: position_score
table:
  filename: ENCFF205OKL.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR000AMA
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR000AMA [TISSUE: Homo sapiens HepG2, TARGET: CTCF]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: IDR thresholded peaks\n\n**audit\\_error**:\
    \ Processed alignments file {ENCFF129CNS|/files/ENCFF129CNS/} processed by ChIP-seq\
    \ ENCODE4 v1.5.1 GRCh38 pipeline has 1959659 usable fragments. The minimum ENCODE\
    \ standard for each replicate in a ChIP-seq experiment targeting CTCF-human and\
    \ investigated as a transcription factor is 10 million usable fragments. The recommended\
    \ value is > 20 million, but > 10 million is acceptable. (See {ENCODE ChIP-seq\
    \ data standards|/data-standards/chip-seq/} )\n\n**audit\\_internal\\_action**:\
    \ Released analysis {ENCAN293JLK|/analyses/ENCAN293JLK/} has in progress subobject\
    \ quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}\n\n**audit\\\
    _internal\\_action**: Released analysis {ENCAN293JLK|/analyses/ENCAN293JLK/} has\
    \ in progress subobject document {1957f40f-d9d1-465b-be12-94371b07d22e|/documents/1957f40f-d9d1-465b-be12-94371b07d22e/}\n\
    \n**audit\\_warning**: Processed alignments file {ENCFF520WEM|/files/ENCFF520WEM/}\
    \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline has 10128882 usable fragments.\
    \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ CTCF-human and investigated as a transcription factor is 10 million usable fragments.\
    \ The recommended value is > 20 million, but > 10 million is acceptable. (See\
    \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\
    \ Replicate concordance in ChIP-seq experiments is measured by calculating IDR\
    \ values (Irreproducible Discovery Rate). ENCODE processed IDR thresholded peaks\
    \ files {ENCFF205OKL|/files/ENCFF205OKL/} processed by ChIP-seq ENCODE4 v1.5.1\
    \ GRCh38 pipeline have a rescue ratio of 1.33 and a self consistency ratio of\
    \ 2.98. According to ENCODE standards, having both rescue ratio and self consistency\
    \ ratio values < 2 is recommended, but having only one of the ratio values < 2\
    \ is acceptable.\n\n**audit\\_warning**: Replicate concordance in ChIP-seq experiments\
    \ is measured by calculating IDR values (Irreproducible Discovery Rate). ENCODE\
    \ processed IDR thresholded peaks files {ENCFF194VBQ|/files/ENCFF194VBQ/} processed\
    \ by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline have a rescue ratio of 1.33 and a\
    \ self consistency ratio of 2.98. According to ENCODE standards, having both rescue\
    \ ratio and self consistency ratio values < 2 is recommended, but having only\
    \ one of the ratio values < 2 is acceptable."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR000AMA
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens HepG2
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0001187/
    perturbed: false
    doi: 10.17989/ENCSR000AMA
    date_created: '2013-11-07T22:16:11.089907+00:00'
    date_released: '2011-02-10'
    submitter_comment: As of February 9th, 2017, the control has been changed to ENCSR055XHN,
      requiring new peaks and signal files.
    target: CTCF
