type: position_score
table:
  filename: ENCFF400QKK.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: DNase-seq_ENCSR000EIK
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'DNase-seq ENCSR000EIK [TISSUE: Homo sapiens frontal cortex tissue male
    adult (27 years) and male adult (35 years)]'
  description: '**status**: released


    **biological\_replicates**: Rep 2


    **summary**: male adult (35 years) male adult (27 years)


    **output\_type**: peaks


    **audit\_internal\_action**: Released analysis {ENCAN379KID|/analyses/ENCAN379KID/}
    has in progress subobject document {5ba1a2cd-7836-49d6-802c-dda409dbd6cc|/documents/5ba1a2cd-7836-49d6-802c-dda409dbd6cc/}


    **audit\_warning**: Signal Portion of Tags (SPOT) is a measure of enrichment,
    analogous to the commonly used fraction of reads in peaks metric. ENCODE processed
    alignment files {ENCFF939YKY|/files/ENCFF939YKY/} processed by DNase-seq ENCODE4
    v3.0.0 GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38 assembly  have
    a SPOT1 score of 0.38. According to ENCODE standards, SPOT1 score of 0.4 or higher
    is considered a product of high quality data. Any sample with a SPOT1 score <0.3
    should be targeted for replacement with a higher quality sample, and a SPOT1 score
    of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally
    acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data
    standards|/data-standards/dnase-seq-encode4/})


    **audit\_warning**: Signal Portion of Tags (SPOT) is a measure of enrichment,
    analogous to the commonly used fraction of reads in peaks metric. ENCODE processed
    alignment files {ENCFF846MVS|/files/ENCFF846MVS/} processed by DNase-seq ENCODE4
    v3.0.0 GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38 assembly  have
    a SPOT1 score of 0.28. According to ENCODE standards, SPOT1 score of 0.4 or higher
    is considered a product of high quality data. Any sample with a SPOT1 score <0.3
    should be targeted for replacement with a higher quality sample, and a SPOT1 score
    of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally
    acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data
    standards|/data-standards/dnase-seq-encode4/})'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR000EIK
    status: released
    assay_term_name: DNase-seq
    simple_biosample_summary: male adult (35 years) male adult (27 years)
    biosample_summary: Homo sapiens frontal cortex tissue male adult (27 years) and
      male adult (35 years)
    replication_type: anisogenic
    biosample_ontology: /biosample-types/tissue_UBERON_0001870/
    perturbed: false
    doi: 10.17989/ENCSR000EIK
    date_created: '2014-01-30T18:56:40.699991+00:00'
    date_released: '2012-08-28'
    submitter_comment: ''
